Kane Biotech Develops DispersinB(R) Monoclonal Antibodies
WINNIPEG, MANITOBA -- (MARKET WIRE) -- 09/21/10 -- Kane Biotech Inc. (TSX VENTURE: KNE), a biotechnology company engaged in the development and commercialization of products that prevent and remove microbial biofilms, is pleased to announce that the development and selection of hybridoma cell lines to produce anti-DispersinB® monoclonal antibodies for a DispersinB® immunoassay has been successfully completed.
DispersinB® is a very active enzyme used in micro quantities. The development of a specific and sensitive monoclonal antibody-based immunoassay method for detection and quantification of DispersinB® in nanograms or micrograms is essential in the product's development. The successful cloning and selection of stable hybridoma cell lines producing an optimal antibody titer is an important step in the development of a DispersinB® enzyme-linked immunosorbent assay (ELISA) kit.
"The DispersinB®-specific ELISA kit will be very useful in studying the release kinetics of DispersinB® enzyme in medical devices and wound care products eluting trace amounts of enzyme," stated Dr. Sri Madhyastha, Vice President-Research and Chief Scientific Officer of Kane Biotech. "Additionally, this kit will be helpful in measuring the concentrations of DispersinB® in nanograms during the enzyme's production by E. coli fermentation."
"This DispersinB® ELISA kit will be complimentary to the current testing of our DispersinB® technology by a number of companies, universities and research institutes all over the world," stated Gord Froehlich, President and CEO of Kane Biotech. "With the development of DispersinB® monoclonal antibodies completed, we will now move forward to completing development of the ELISA kit."
About Kane Biotech Inc.
Kane Biotech is a biotechnology company engaged in the development and commercialization of products that prevent and remove microbial biofilms. Biofilms develop when bacteria and other microorganisms form a protective matrix that acts as a shield against attack. When in a biofilm, bacteria become highly resistant to antibiotics, biocides, disinfectants, high temperatures and host immune responses. This resiliency contributes to human health problems such as medical device and wound associated infections and tooth decay.
Kane Biotech uses patent protected technologies based on molecular mechanisms of biofilm formation/dispersal and methods for finding compounds that inhibit or disrupt biofilms. The Company has evidence that these technologies have potential to significantly improve the ability to prevent and/or destroy biofilms in several medical and industrial applications.
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These risks and uncertainties should be considered carefully and prospective investors should not place undue reliance on the forward-looking statements. Although the forward-looking statements contained in this press release are based upon what management believes to be reasonable assumptions, Kane cannot provide assurance that actual results will be consistent with these forward-looking statements. Kane undertakes no obligation to update or revise any forward-looking statement.
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Contacts: Kane Biotech Inc. Gord Froehlich President & Chief Executive Officer 204-477-7592 204-453-1314 (FAX) ir@kanebiotech.com www.kanebiotech.com
Released September 21, 2010